*Corresponding author:Beata Smolarz, Laboratory of Cancer Genetics, Department of Pathology, Institute of Polish Mother’s Memorial Hospital, Rzgowska 281/289, 93-338 Lodz, Poland
Received: June 14, 2018; Published: July 18, 2018
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Background: Although screening algorithm has introduced an efficient tool to tackle cervical cancer, both morbidity and mortality in this disease are still a major concern in medicine. It has been already proven that Human papillomavirus (HPV) infection promotes the development of precancerous lesions and eventually leads to cervical cancer. This study aimed at analysis of the prevalence of high risk HPV DNA (HR HPV) in females of Lodz region, central Poland.
Methods: In this study we employed Cobas 4800 HPV test to detect the HR HPV in 240 cervical smear samples.
Results: 48 patients (20%) proved to be positive regarding HPV-16 DNA and 32 patients (13%)-regarding HPV-18 DNA. In overall assessment, in 80 patients (33%) we have detected oncogenic HPV subtypes, other than the two abovementioned.
Conclusion: Cobas 4800 HPV test is a viable, effective, easy and quick tool in detecting high risk HPV DNA.
Keywords: HPV; Cervical Cancer; Genotyping