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Research ArticleOpen Access

Exposure to Phthalates of Critically Ill Children: a Pilot Single Center Study

Volume 6 - Issue 2

William Davidson Urbain1, Philippe Jouvet1,2, Maria P Vélez3, Pierre Ayotte4 and Patricia Monnier*5

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    • 1Research Center of Ste Justine Hospital, Canada
    • 2Pediatric ICU, Sainte-Justine Hospital, Canada
    • 3Department of Obstetrics and Gynecology, Queen’s University, Kingston
    • 4Centre de toxicologie du Québec, Institut national de santé publique du Québec, Canada
    • 5Department of Gyneco-Obstetrics, MUHC Reproductive Center, Canada

    *Corresponding author: Patricia Monnier, MUHC Reproductive Center, 200-88 de Maisonneuve Blvd East, Montreal, Qc, H2L 4S8

Received: June 20, 2018;   Published: July 03, 2018

DOI: 10.26717/BJSTR.2018.06.001322

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Abstract

Introduction:Medical devices used in Pediatric Intensive Care Units (PICU) are mostly made of plastic containing plasticizers that can leach out into the blood. We conducted a pilot study to assess exposure to phthalates in PICU.

Methods:Phthalates metabolites levels were measured in urine of critically ill children at admission and Day 4. Plastic medical equipment required for each patient was also recorded.

Results: All sixteen patients had high levels of phthalates metabolites in urine and infants had higher levels than adolescents. Despite plastic exposures, no increase in phthalates metabolites between admission and day 4 was observed.

Conclusion: Children in PICU have a high degree of phthalates exposure

Keywords: Children; Intensive Care; Phthalates; Prospective Study

Abstract| Introduction| Methods| Results| Discussion| Conclusion| References|