Patients with Idiopathic Inflammatory Myopathies and Primary involvement of Heart Muscle and Cardiovascular Complications

Aleksandra Opinc¹, Marcin Makowski² and Joanna Makowska*¹

Received: May 28, 2018;;   Published: June 08, 2018

DOI: 10.26717/BJSTR.2018.05.001184

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Abstract

Idiopathic inflammatory myopathies are rare connective tissue disorders, in which inflammatory process affects mainly skeletal muscles leading to their progressive weakness. However internal organs can be affected as well, deteriorating the course of disease. We present cases of two patients with cardiac manifestations as predominant symptoms of idiopathic inflammatory myopathies. In both cases arrhythmia was the leading symptom preceding diagnosis of myositis.

Keywords: Myositis; Myopathy; Arrhythmia

Abbreviations:IIM: Idiopathic Inflammatory Myopathy; PM: Polymyositis; DM: Dermatomyositis; IBM: Inclusion Body Myositis; MRI: Magnetic Resonance Imaging; CRP: C-Reactive Protein; CK: Creatine kinase; CK-MB: Creatine kinase Muscle-Brain isoenzyme; DDD pacemaker: Dual Chamber pacemaker; CRT-P: Cardiac Resynchronization Therapy Pacemaker; LV: Left ventricle; LVEF: Left Ventricle Ejection Fraction; LDH: Lactate Dehydrogenase; ANA: Antinuclear antibodies; ESR: Erythrocyte Sedimentation Rate; pANCA: Perinuclear Anti-Neutrophil Cytoplasmic Antibodies; ECG: Electrocardiography; CHF: Congestive Heart Failure

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