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Microneurography of Peripheral Nerves in Mice: An Old Approach Applied to the Novel Concept of Neural Modulation of Immune Organs in Cardiovascular Diseases

Volume 2 - Issue 5

Lorenzo Carnevale*1, Marialuisa Perrotta2 and Giuseppe Lembo1,2

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    • 1Department of Angiocardioneurology and Translational Medicine, Italy
    • 2Department of Molecular Medicine, Sapienza University of Rome, Italy

    *Corresponding author: Lorenzo Carnevale, Department of Angiocardioneurology and Translational Medicine, IRCCS Neuromed, Pozzilli (IS), Italy

Received: February 20, 2018;   Published: February 28, 2018

DOI: 10.26717/BJSTR.2018.02.000806

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Microneurography in small animals has proven to be a fundamental tool to investigate novel concepts of immune modulation by the autonomic nervous system. Major discoveries in the field pushed toward new investigation in the cardiovascular pathophysiology, to explore the relations between immune organs such as the spleen and hypertension. Given the variety of nerves of interest a great effort has to be put in the standardization of technical, experimental setup and analysis procedures.

Keywords: Microneurography; Splenic Nerve Recording; Neuroimmune Modulation; Sympathetic Nerve Recording

Abstract| Introduction| Technical Setup and Experimental Procedures| Analysis| Conclusion| References|