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Case ReportOpen Access

Benign Metastasizing Leiomyoma of the Lung: Lesion Regression after Surgical Ovariectomy

Volume 2 - Issue 4

Rocco Delfanti*1, Luigi Conti1, Claudia Biasini2 and Patrizio Capelli1

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    • 1Department of Surgery, G Da Saliceto Hospital, Piacenza, Italy
    • 2Department of Oncology, G. Da Saliceto Hospital, Piacenza, Italy

    *Corresponding author: Luigi Conti, Department of General, Vascular and Breast Surgery, Piacenza, Italy

Received: February 19, 2018;   Published: February 26, 2018

DOI: 10.26717/BJSTR.2018.02.000800

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Benign metastasizing leiomyomas are a rare disease occurring in the lung of pre-menopausal women with a history of benign leiomyoma of the uterus; they are discovered incidentally because often asymptomatic and should be differentiated from low grade uterus sarcoma. Tumor cells are positive for estrogen and progesterone receptors so therapy is based on ovarian hormonal suppression, performed chemically or by surgical ovariectomy. We present the case of a 40-year old woman with a history of benign uterine leiomyoma who was admitted to the Oncological Department to investigate the presence of solid nodules in lungs, found accidentally on chest radiogram. She underwent to hysterectomy and bilateral ovariectomy; specimen confirmed only the persistence of benign uterine leiomyoma.

No further therapy was proposed and the follow up was managed with clinical visit and thoracic CT scan every six months for the first year, twelve monthly then. BML is a rare disease, reported as single cases occasionally in the literature. Lungs are the organs most often involved and radiologically the lesions tend to present as multiple, bilateral, well circumscribed solid nodules of various dimensions. Interesting is the significant response in the regression of dimension and number of lung nodules, due only to hormonal suppression and the persistence of the response along a period of four years, this confirming both his benign nature and the influence of ovarian hormonal activity on BML cells.

Keywords: Benign Metastasizing Leiomyoma-lung-uterine leiomyoma

Abbreviations: BML: Benign Metastasizing Leiomyoma; CT: Computed Tomography; LGUS: Low Grade Uterus Sarcoma ;VATS: Video-Assisted Thoracic Surgery

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