*Corresponding author:
Fausto Baldanti, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, ItalyReceived: February 02, 2018; Published: February 20, 2018
DOI: 10.26717/BJSTR.2018.02.000776
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Solid organ transplant recipients (SOTRs) are at high risk of viral opportunistic infections, especially during the first six months posttransplant. Human cytomegalovirus (HCMV) remains one of the most important pathogens in transplant recipients, despite the great efforts in diagnosis and effective antiviral therapies. Immunological monitoring could be useful in order to guarantee a better management of the patients. In this setting, several methods have been employed. The review summarizes the most important approaches in immunological monitoring of HCMV-specific T-cell response in transplant setting.
Keywords: Human cytomegalovirus; Transplant; T-cell response; Quantiferon; Elispot assay
Abbreviations: SOTR:Solid Organ Transplant Recipients; HCMV: Human Cyto Megalo Virus, IFNγ: interferon gamma