*Corresponding author:Ibrahim Rudhani, Medicinal Faculty, university of Prishtina, 10000 Prishtina, Kosovo
Received: January 27, 2018; Published: February 09, 2018
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In this study the antibacterial efficiency of ethanol extract from Salvia Officinalis (L.) growing wild in Kosovo were examined. Ethanol extract was tested against two gram positive bacteria Staphylococus aureus (clinical isolate), Listeria monocytogenes (clinical isolate) and one gram negative bacteria Escherichia coli (clinical isolate). The antibacterial activity was determined by using agar disc diffusion method. The inhibition zone of extract was compared to that of penicillin G. The ethanol extract showed activity in all of the concentrations 1, 3 and 5 mg/ mL towards E. coli, S. aureus and L. Monocytogenes. Ethanol extract of the plant with concentration 5 mg/mL showed a stronger antibacterial activity towards bacteria S. aureus with inhibition zone of 9 mm. The antibacterial activity of the S. officinalis (L.) was due to the presence of various secondary metabolites such as phenols and flavonoids. Hence, this plant can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals.
Keywords: Salvia Officinalis (L.); Antibacterial activity; Agar disk diffusion method; Ethanol extract