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Research ArticleOpen Access

Development of a Novel Suture-less Nerve Coaptation Device

Volume 2 - Issue 2

Angel F Farinas*, Kevin Saladino, Alonda C Pollins MLI, Nancy L Cardwell BS and Wesley P Thayer

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    • Department of Plastic Surgery, Vanderbilt University Medical Center, USA

    *Corresponding author: Wesley P Thayer, Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, USA

Received: December 11, 2017;   Published: February 05, 2018

DOI: 10.26717/BJSTR.2018.02.000728

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Background: Creating a barbed sutureless coaptation device will provide a simple and standardized alternative to nerve repair decreasing donor’s morbidity.

Methods: Autodesk Fusion 360 program was used to design the prototype and was produced on a Monoprice Maker Ultimate 3D Printer. A total of 89cm of caprine and canine vagus nerve were harvested, trimmed at 4cm segments and divided in four groups depending on the device used or intervention: Hollow, Ridged, Sutured and Barbed. An Instron 5542machine was used to calculate the energy at break (gf/mm).

Results: The energy at break of the Hollow group was 41.23 (±5.00) gf/mm, more than double for the Ridged: 107.024 (±29.06) gf/mm, and even higher for the Sutured: 392.69 (±66.24) gf/mm. But the Barbed group outperformed all groups with 1227.36 (250.88) gf/mm, with no statistical significance when compared the suture group (p>0.05).

Conclusion: The Barbed device was more resistant than the other groups in maintaining the nerve in position. Our prototype has the potential to become a viable alternative to peripheral nerve repair due to its ease of application and lack of a need for microsurgery for coaptation..

Keywords: Coaptation; Suture-Less; Conduit; Bioprinting; Barbed

Abstract| Introduction| Materials and Methods| Results| Discussion| Conclusion| References|