Esophagitis Dessicans Superficialis (EDS) refers to a rare and unique lesion of the esophagus characterized by sloughing of esophageal
mucosa. A benign condition, it is thought to be a mucosal reaction to various types of insults or a mucosal allergic response. Various clinical
presentations, endoscopic appearances and associations with systemic diseases have been described in literature. We report 4 consecutive
cases of this rare condition in our endoscopy practice with varying endoscopic characteristics and present a literature review of EDS.