We report the case of a 66-year-old patient, followed for a high-grade urothelial carcinoma for 2 years, initially mesa static at the level of the prostate. The patient was then put on neoadjuvant chemotherapy, but he was lost to follow-up and presented himself after 5 months, with extension of the tumor to the gallbladder, and the urethral masses , the internal obturator muscle and bilateral external iliac lymphadenopathy, as well as adrenal metastasis, with an examination of oncologists the presence of a skin tumor in the right thoracic level, hence a dermatological opinion was requested. A dermatological examination on an objectified presence of a pigmented tumor of 5/6 cm of large, an ulcerated and bleeding surface, sitting at the level of the anterior surface of the thorax, on the right side (Figure 1). At the dermoscopy we had pigmented areas without structures, with the presence of a polymorphic vascularization made of arborising vessels as well as tortuous vessels (Figure 2), in front of this aspect associated with the clinical context we first thought to a skin metastasis bladder tumor, and a skin biopsy was performed confirming this diagnosis. The patient was then kept on palliative chemotherapy based on cisplatin + gemcitabine and died 2 months later.
Only 5.3% of all malignancies lead to cutaneous metastasis. Out
of these, 1.34% are linked to underlying genitourinary malignancy;
bladder cancer accounts for 0.84% of these  with a limited number
of published cases, It usually metastasizes to regional lymph nodes,
liver, lungs and bones  Large 20-year retrospective Taiwanese
study found only 2 cases of skin metastases among 911 patients
with bladder and ureter cancer  and Kishi, et al.  reported that
66.7% of patients with T3 and T4 tumors had metastatic disease.
Cutaneous involvement from bladder cancer is achieved by direct
tumor invasion, hematogenous routes, lymphatic spread, and direct
seeding due to iatrogenic implantation .Iatrogenic implantation
is the most common cause of seeding outside of the urinary tract
and its due to surgical treatment of these tumors, including
cystectomy, partial cystectomy, TURBT, and other procedures .
The clinical appearance of these lesions varies and may mimic other
dermatologic diseases. The lesions can be solitary or multiple, and
can have a nodular, fibrotic, and inflammatory appearance.
In urological cancer with cutaneous metastasis,several aspects have been described in the literature,like , A cutaneous erysipelas-like lesion  Zosteriform cutaneous metastases  or Herpetiform cutaneous metastases , but the most common clinical picture is an infiltrated plaque or nodule  Ulcerated swelling, subcutaneous nodules, violaceous papules, and ulcerated plaques have been reported  in our patient the appearance was that of a large tumor with ulcerated surface. Dermoscopy of skin metastases has been recently reported in the literature , the most reported sign was a polymorphic vascularization made of arborising vessels, as well as serpiginous, but these aspects were not retained as specific, since they can be found even in front of a primary skin tumor, such as melanoma or squamous cell carcinoma. Local excision, radiotherapy, chemotherapy, immunological and combination therapy have been reported in previous studies . Due to the poor outcomes of these patients, the treatment options are limited and primarily supportive in nature. The prognosis of any cancer with cutaneous metastasis is poor; with regard to bladder cancer with cutaneous metastasis, median survival time is < 12 months .
We report a new case of skin metastasis of a bladder tumor, in the form of a pigmented tumor in a patient with multiple visceral metastases. Although cutaneous metastasis is a rare dermatological condition, cutaneous metastasis should be included in the differential diagnosis of tumoal lesion. Skin biopsy should be performed to prevent misdiagnosis. For the patients with urologic malignancies, we suggest that all urologists should increase attention to the physical examination of the skin because skin lesions can be the first sign of silent or recurrent urologic malignancies.
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