Abstract

In this work, we obtain the parameters of the actuator for nano biomedical research. We have mathematical model of the actuator with the piezoelectric or magneto strictive effect.

Keywords: Piezoelectric actuator, Magneto strictive actuator, Electromechanics, Parameter.

Introduction

Actuator for nano biomedical research is used to nanomanipulations in the scanning microscope, the nanoliter pump, the gene manipulator, the cell penetration tool, the microsurgery [1−16]. We obtain the transfer functions and the characteristics of the actuators on the piezoelectric and magneto strictive effect for control system of the nano deformation for nano biomedical research [17−28].

Transfer function

The equation of electromechanics [8, 11] for relative deformation S_i of the piezoelectric or magneto strictive actuator has the form

where are the module, the control parameter, the elastic compliance and the mechanical stress, and i, j,m are the indexes. We have the second order differential equation [8, 12, 14] for the actuator in the form

and the transfer function W( p) of the actuator

W( p) = Ξ( p) / Ψ( p)

where Ξ(p) ,Ψ( p) are transforms of Laplace the displacement and the control parameter, p, γ , x are the conversion parameter, the propagation coefficient, the coordinate.

We drew model of the actuator from decision the equation of electromechanics and the second order differential equation [12- 15]. In result we have the mathematical model and the scheme of the actuator for nano biomedical research on Figure 1 with the piezoelectric or magneto strictive effect in the form

where Ξ¹ (p), Ξ² (p), F¹( p), F²( p) are transforms of the displacements and the forces of the faces, M₁, M₂, l are the mass and the length.

We receive the transfer function of the transverse piezoelectric actuator in the form

At d₃₁ = 2∙10^-10 m/V, h /δ = 20, U = 50 V, M₂ = 4 kg, C₁₁^E = 2∙10⁷ N/m, C_e = 0.5∙10⁷ N/m we obtain the parameters of actuator k_t = 3.2 nm/V, ξ₂ (∞) = 160 nm, T_t = 0.4∙10^-3 s.

Figure 1: Structural scheme of actuator for nano biomedical research.

Conclusion

In this work, we receive the transfer functions and the parameters of the actuator for the control system of the nano deformation for nano biomedical research. We obtain the mathematical model of the actuator from decision the equation of electromechanics and the second order differential equation.

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Abstract

A needle for obtaining a solid core (trephine) bone marrow biopsy sample from the posterior ilium is described. The needle is comprised of a hollow stainless-steel tube whose front-end diameter is reduced in comparison with the proximal segment. At its terminus the needle is also beveled and has six circumferentially spaced facets thereby forming a sharp cutting edge. The segment of the tube between the longer wider portion of the hollow tube and its smaller reduced diameter front end portion has a series of diamond shaped serrations/flutes on its surface which offer enhanced cutting ability as with a saw to assist in easy penetration of the needle through the dense cortical bone and into the marrow cavity.

Keywords: Single-use bone marrow biopsy needle; Core retention bone marrow biopsy needle; Bone marrow biopsy; Needle