Preclinic Evaluation and Characteristics of a Novel Nasal Medical Matrix Derived from Polyvinyl Alcohol Foam for Protecting Respiratory Tract Via A Designed Microparticle-Detecting System Combining Laser Resources of 532 Nm with Low Light Sensors

obtained to provide preclinic evidences of assistance for protecting respiratory tract. In usual, the filtration film or filter membrane was employed in the medical device or mask for protecting respiratory tract. The filtration film or filter membrane could be a filtration Huang. Preclinic Evaluation and Characteristics of a Novel Nasal Medical Matrix Derived from Polyvinyl Alcohol Foam for Protecting Respiratory Tract Via A Designed Microparticle-De-tecting System Combining Laser Resources of 532 Nm with Low Light Sensors. Biomed J Sci & Tech Res 27(5)-2020. BJSTR. MS.ID.004568. A novel nasal medical matrix derived from polyvinyl alcohol foam for protecting respiratory tract was designed and prepared. Further, evaluation and characteristics of the nasal medical matrix for protecting respiratory tract was carried out by using a designed microparticle- detecting system, which combined laser resources with low light sensors. A series of mmicroparticle-detecting images with high picture quality could be obtained even in a low light environment, which provide preclinic envidences for assistance of protecting respiratory tract.


Introduction
The design of medical devices could be applied and developed  [1][2][3][4][5][6]. The surface modification could be considered to change the surface characteristic and microenvironment of materials for specific clinic demand [7,8]. High permeability of protecting medical matrix such as polyurethane (PU) matrix or non-woven matrix could be employed for the clinic application of masks. However, polyurethane or non-woven medical matrix showed poor tissue anti-adhesion property, which would be a clinic risk for wound managements. Polyvinyl alcohol showed well clinic applications because of good cell or tissue anti-adhesion property and high permeability no whether the matrix in the dried state or in the wet state [9].
A design of novel nasal medical matrix derived from polyvinyl alcohol foam for protecting respiratory tract was studied. Further, evaluation and characteristics of the nasal medical matrix was carried out by using a designed microparticle-detecting system, which combined laser resources with low light sensors. A series of mmicroparticle-detecting images with high picture quality would be obtained to provide preclinic evidences of assistance for protecting respiratory tract. In usual, the filtration film or filter membrane was employed in the medical device or mask for protecting respiratory tract. The filtration film or filter membrane could be a filtration layer or an absorption layer in the medical device or the mask or the matrix. In this report, we propose a series of novel techniques and medical devices for protecting respiratory tract. For the design of new medical devices for protecting respiratory tract, selections of suitable materials for clinical applications of protecting respiratory tract such as ppolyvinyl alcohol foam or polyurethane foam were substantially considered and employed [9]. Furthermore, the biological and clinical evaluations of materials and medical devices by using polyvinyl alcohol foam (PVAF) must be considered for the application and design [9]. Preclinical evaluation of new polyvinyl alcohol foam (PVAF) nasal matrix could be established by determining penetrating microparticles, water permeability, and macroporosityl property of resulting samples. A new microparticle-detecting system was designed by using some key modules such as a laser resource of 532 nm, an optical sensor photomultiplier, an image processing system, an optical scattering wall, a limiting module, and a mmicroparticles supply system to build up a new way for ppreclinical evaluation of protecting respiratory tract. Also, ppreclinical evaluation of the medical matrix by using the designed microparticle-detecting system, which combined laser resources with low light sensors.

Result and Discussion
In this study, a novel nasal medical matrix derived from polyvinyl alcohol foam for protecting respiratory tract was   (Figure 2 E). However, the evolution of protecting respiratory tract is difficult to be carried out because the water micro drops and solid microparticles would be detected together by the traditional system. For this reason, a new detecting system which catch the solid particles only must be designed. So, a novel mmicroparticle-detecting system were designed and employed to provide a high mmicroparticle-detecting picture quality even in a low light environment. The highly sensitive image of the penetrating water micro drops, and nasal medical matrix derived from polyvinyl alcohol foam for protecting respiratory tract was showed in Figure 3. There is no image of microparticles and micro drops in the Figure 3, which imply that water micro drops could not be observed in the new microparticle-detecting system. Nasal medical matrix. B.
A microparticles storage. C.
Air supply. D.

F.
A water films. G.
Air flow.

H.
Microcells.  Figure 4A), an optical sensor photomultiplier ( Figure 4B), and an image processing system ( Figure 4C) to build up an image forming and processing environment. In particular, an optical scattering wall ( Figure 4D) derived from a laser source ( Figure 4A) was designed to catch the image of penetrating microparticles ( Figure   4E), which pass through the nasal matrix medical devices fixed in the limiting module ( Figure 4H). The direction of airflow is perpendicular to the optical scattering wall ( Figure 4D). In usual, large amounts of penetrating microparticles were detected through a surgical mask fixed in the limiting module ( Figure 4H). No   humidifical nasal medical matrix could further provide hydro-absorption behaviors to constructure a besieged microparticles route. Also, a new microparticle-detecting system was employed to provide a high microparticle-detecting picture quality even in a low light environment. The images with a high picture quality were showed in the ( Figures 5A-D). Figure 5A showed an image resulted from the penetrating microparticles and two bound surgical masks. Large amounts of penetrating microparticles could be detected. Figure 5B showed an image resulted from the penetrating microparticles and three bound surgical masks. Small amounts of penetrating microparticles could be detected with the microparticle-determining system. If N95 mask was employed in the study, few penetrating microparticles would still be observed.
There is not any penetrating microparticle was found through novel nasal medical matrix derived from polyvinyl alcohol foam ( Figure   5D). The results provide good preclinic evidences for assistance of protecting respiratory tract via the designed microparticledetermining system.

Conclusion
A novel nasal medical matrix derived from polyvinyl alcohol foam for protecting respiratory tract was designed. Further, evaluation and characteristics of the nasal medical matrix for protecting respiratory tract was successfully carried out by using a designed microparticle-detecting system, which combined laser resources (532 nm) with low light sensors. A series of microparticledetecting images with high picture quality could be obtained even in a low light environment, which provide preclinic evidences for assistance of protecting respiratory tract.