Single Coronary Anomaly: The Left Main Coronary Artery Originating from the Proximal of Right Coronary Artery

Coronary artery anomalies (CAAs) are present at birth but are usually asymptomatic and are found during coronary angiography or multi-slice computed tomography (MSCT) detection. Their prevalence is less than 1.3% based published series [1-3]. The most common coronary anomaly is separate origination of the left anterior descending coronary artery (LAD) and left circumflex coronary artery (LCX) from left sinus of Valsalva. The second most common anomaly is origination of the LCX artery from the right coronary artery (RCA) or right sinus of Valsalva. Herein, we present one case of single coronary artery anomaly that the anomalous left main coronary artery (LMCA) arises from the proximal of the right coronary artery. It is rare case and very important to our clinical practices.


Introduction
Coronary artery anomalies (CAAs) are present at birth but are usually asymptomatic and are found during coronary angiography or multi-slice computed tomography (MSCT) detection. Their prevalence is less than 1.3% based published series [1][2][3]. The most common coronary anomaly is separate origination of the left anterior descending coronary artery (LAD) and left circumflex coronary artery (LCX) from left sinus of Valsalva. The second most common anomaly is origination of the LCX artery from the right coronary artery (RCA) or right sinus of Valsalva. Herein, we present one case of single coronary artery anomaly that the anomalous left main coronary artery (LMCA) arises from the proximal of the right coronary artery. It is rare case and very important to our clinical practices.

Case Presentation
A 67-year-old man presented progressive chest pain after physical exertion for ten months, he was admitted to our hospital on November 6th, 2009. He suffered from diabetic mellitus and hypertension for eight years. Coronary angiogram was performed through trans-radial approach. An angiogram demonstrated a single coronary artery: the LMCA originating from the proximal of right coronary artery and then dividing into the left anterior descending artery (LAD) and the left circumflex artery (LCX). In LAO projection there was borderline lesions at the body of the LMCA, it was about 1.5cm lesions in length. There was mild narrowing in the mid of LAD segment, and the LCX, RCA were patent (Figures 1-3). As the lesions of LMCA are borderline, neither percutaneous coronary intervention (PCI) nor coronary artery bypass graft surgery (CABG) was performed, the patient was treated by oral medications including aspirin, nitroglycerine, atorvastatin and ACEI drugs. He was free of chest pain during a 24-month follow-up. In order to

Discussion
Coronary artery anomalies are present at birth but are usually asymptomatic and are found during coronary angiography or multislice computed tomography (MSCT) detection. Their prevalence is less than 1.3% based published series [1][2][3][4]. The most common coronary anomaly is the left circumflex artery (LCX) arising from the proximal of right coronary artery (RCA). This variant is benign. c) The anomalous left main coronary artery originates from the proximal of right coronary artery.
The anomalous coronary artery is first designated with "R" or "L" depending upon whether the ostium is located in the right pulmonary artery, i.e., "anterior," "between," "septal," "posterior," and "combined." In this series, the "septal" subtype was the most common, whereas the "between" type was rare [2][3][4][5]. However, the left main coronary artery (LMCA) deriving from the proximal of the RCA is extremely rare. Tt's prevalence is less than 0.047% [1]. Seen in the left ventriculogram, The LMCA may course in front of pulmonary artery (anterior course), through the septum (septal course), between the aorta and pulmonary artery trunk (interarterial course), or behind the aorta (retroaotic course) [6].
The case we presented is the anomalous LMCA arising from the proximal of right coronary artery (RCA). The origin and course of anomalous LMCA was confirmed by MSCT technique [7], the results demonstrated that the anomalous LMCA coursed between the aorta and left atrium. The anomalous LMCA was classified as R-II P subtype (retroaotic course). We bring forth the case in an attempt to highlight their significance. The anomaly is considered to be an independent risk factor for adverse cardiovascular events including sudden cardiac death and dealing with their lesions is a challenge to cardiologists. Coronary anomalies are usually detected during coronary angiography. However, X-ray angiography is limited by its inability to provide information regarding the spatial orientation of the anomalous artery with regarding to the surrounding cardiovascular structures [4,5]. With the help of science and technology, MSCT technique has the potential to accurately visualize the coronary artery [7] and clearly demonstrate the surrounding cardiovascular structures of the anomalous coronary artery [8].
In the present case, the MSCT images clearly demonstrated the origin and course of the anomalous left main coronary artery. It was belonged to R-II P subtype (retroaotic course). So we bring forth the case in an attempt to highlight their significance, and make cardiologist understood what important the anomalies are. A single coronary artery provides a unique challenge to cardiologists when dealing with critical lesions of coronary vasculature, which would otherwise have been easily amenable to angioplasty. Presence of coronary artery anomalies create challenges during coronary angiography, Percutaneous coronary interventions, and coronary artery bypass graft surgery [9]. It is very important to interventional cardiologist and cardiac surgeon in clinical practices [10].