Research ArticleOpen Access

Autologous Platelet Concentrate Preparations in Dentistry

Volume 8 - Issue 5

Ola M Ezzatt*

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- Associate Professor of Oral Medicine and Periodontology, Faculty of Dentistry, Ain-Shams University, Egypt
*Corresponding author: Ola M Ezzatt, Associate Professor of Oral Medicine and Periodontology, Faculty of Dentistry Ain-Shams University Cairo, Egypt

Received: August 27, 2018; Published: September 07, 2018

DOI: 10.26717/BJSTR.2018.08.001706

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Abstract

Platelet concentrates are blood derivatives prepared from the patient’s own blood in which the activated platelets become trapped within a fibrin matrix scaffold and release growth factors and cytokines involved in the key processes of tissue regeneration; including cell proliferation and differentiation, extracellular matrix synthesis, chemotaxis and angiogenesis. These processes found to promote healing in both soft and hard tissues which led to successful therapeutic applications in medical and dental fields over the last two decades. Based on differences in centrifugation speeds and times, adding chemicals, and the selection of supernatants and precipitates; various preparations have been produced with different fibrin network structures, leukocyte content and growth factors and subsequent different physical and physiological properties and applications. The biology behind, the protocols for preparation and the science based evidence applications of different platelet concentrates in various fields of dentistry will be reviewed.

Keywords: Platelet Concentrates; Periodontal Regeneration; Centrifugation Protocol

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