Clinical and Neurocognitive Outcome Evaluation
In locked-in Syndrome

Silvia Marino; Francesco Corallo; Cettina Allone; Caterina Formica; Antonella Alagna; Antonino Todaro; Patrizia
Pollicino; Carmela Rifici; Edoardo Sessa

doi:10.26717/BJSTR.2018.12.002204

Case ReportOpen Access

Clinical and Neurocognitive Outcome Evaluation In locked-in Syndrome

Volume 12 - Issue 1

**Silvia Marino*, Francesco Corallo, Cettina Allone, Caterina Formica, Antonella Alagna, Antonino Todaro, Patrizia Pollicino, Carmela Rifici and Edoardo Sessa**

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- IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy

Received: November 23, 2018; Published: December 13, 2018

DOI: 10.26717/BJSTR.2018.12.002204

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Abstract

We reported a case of Locked-in syndrome, who underwent a specific clinical and neuropsychological battery, assessing verbal memory, linguistic comprehension, perception, executive functioning and abstract reasoning, and the quality of life, at baseline and after two months. This battery was adapted to get yes/no responses through the eye movements. Comparing the total raw scores of all tests at T0 and T1, we found validity features values above 0.80, considered indicative of good agreement. We can hypothesize that the clinical and neuropsychological battery we used could be validated for Locked-in patients, even if more data are requested.

Keywords :Locked-in Syndrome; Neuropsychological Assessment; Outcome Evaluation

Abbreviations : LIS: Locked-in Syndrome; MRI: Magnetic Resonance Imaging; ICC: Intraclass Correlation Coefficient