Review ArticleOpen Access

Oral Signs of Helicobacter Pylori- Review of Clinical Outcomes

Volume 8 - Issue 2

**Damla Aksit Bicak*¹ and Serap Akyuz²**

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- ¹Department of Pediatric Dentistry, Near East University, Turkey
- ²Department of Pediatric Dentistry, Near East University, Turkey
*Corresponding author: Damla Aksit Bicak, Near East University, Faculty of Dentistry, Department of Pediatric Dentistry, Near East Boulevard, ZIP: 99138, Mersin 10 - Turkey

Received: August 21, 2018; Published: August 24, 2018

DOI: 10.26717/BJSTR.2018.08.001635

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Abstract

Helicobacter pylori (H. pylori) infection is the most common chronic bacterial infection worldwide and it plays a very important role in the pathogenesis of peptic ulcer, gastric carcinoma, and lymphoid tissue lymphoma. High reinfection rates after successful eradication treatments make the oral cavity a possible reservoir area for the survival of the bacterium. Therefore, the relationship between H. pylori and oral/gastric diseases is being investigated and has become a remarkable issue in recent years. In the oral cavity, H. pylori was first isolated from a dental plaque sample of a patient with gastric H. pylori in 1989. Investigation into the relationship of H. pylori with oral diseases has shown that oral H. pylori may cause halitosis, glossitis, recurrent aphthous stomatitis and dental caries. Hence, the aim of this review is to demonstrate the relationship between H pylori and oral diseases in the context of the previous/latest research.

Keywords: Helicobacter Pylori; Dental Plaque; Saliva; Halitosis; Oral Diseases

Abbreviations: PCR: Polymerase Chain Reaction; VSC: Volatile Sulfur Compounds; P. gingivalis: Porphyromonas Gingivalis; T. denticola: Treponema Denticola; T. forsythia: Tannerella Forsythia; P. intermedia: Prevotella Intermedia; RAU: Recurrent Aphthous Ulcers; RAS: Recurrent Aphthous Stomatitis; (H. pylori): Helicobacter Pylori