Research ArticleOpen Access

Evaluation of Quality Parameters of Three Different Marketed Brands of Yogaraj Guggulu Vati: A Polyherbal Formulation

Volume 6 - Issue 4

**Princy Agarwal¹*, Rajat Vaishnav¹ and Mahendra Singh Ranawat²**

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- ¹Department of Quality Assurance, Bhupal Nobles Institute of Pharmaceutical Sciences, B N University, Sevashram Road, India
- ²Faculty of Pharmacy, B N University, Sevashram Road, India
*Corresponding author: Princy Agarwal, Department of Quality Assurance, Bhupal Nobles Institute of Pharmaceutical Sciences, BNUniversity,Sevashram Road, Udaipur-313001, Rajasthan, India

Received: June 25, 2018; Published: July 09, 2018

DOI: 10.26717/BJSTR.2018.06.001372

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Abstract

YogarajGugguluvati is one of the most commonly used polyherbal formulation in Ayurvedic clinical practice since ages for the ailments of various bone disorders.

Objective: The present work was carried out in order to evaluate comparatively three different and popular formulations of YogarajGugguluVati to confirm their quality and also to highlight the variations that may be present in them.

Methods: Comparative assessment of three different and popular marketed formulations of YogarajGugguluVati was carried out for their organoleptic, pharmaceutical, physicochemical and phytochemical properties as per the methods prescribed in Pharmacopoeias.

Results: The observations reveal that all the parameters of three brands of YogarajGugguluVati had considerable differences in their values. The value of water soluble and alcohol soluble extractives of Brand A was very much higher and lesser than the standard values respectively. The pH of all the tablets was also higher than that of the standard values. The Hardness and Disintegration time of the tablets of Brand B was also very high than the other two brands. The tablets of Brand A also failed the weight variation test.

Conclusion: It can be concluded from the overall results that phytochemical and analytical evaluation and standardization of all the formulations should be performed strictly on all formulations so as to optimize the final product according to the standards, which would otherwise affect the therapeutic activity of the product.

Keywords: Quality Evaluation; YogarajGugguluVati; Pharmaceutical Evaluation;Physico-Chemical Evaluation; Phytochemical Evaluation; Heavy Metal Analysis

Abbrevations: API: Ayurvedic Pharmacopoeia of India; IP: Indian Pharmacopoeia; Pb: Lead;Cd: Cadmium