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ISSN: 2574 -1241
ISSN: 2574 -1241
Received: April 09, 2018; Published: April 17, 2018
DOI: 10.26717/BJSTR.2018.03.000967
Weight loss is frequent in patients with Alzheimer’s disease (AD), even in early disease stage [1]. Therefore, weight loss is a significant predictor of mortality in AD patients. The etiology of AD-associated weight loss is multifactorial, occurring when energy expenditure exceeds energy intake [2]. In addition, the loss of skeletal muscle protein, one of the causes of weight loss, occurs by an imbalance between the rate of protein synthesis and degradation [3]. Therefore, many studies have examined energy expenditure, energy intake, body composition, and other genetic factors in relation to weight loss in AD patients. This mini-review further discusses the factors leading to weight loss in AD patients.
Keywords: Alzheimer’s Disease; Weight Loss; Energy Expenditure; Energy Intake
International Association of Landscape Archaeology, Czech Glass Society, Czech Republic
Department of Chemistry, Semenov Institute of Chemical Physics, USSR Academy of Sciences, Moscow, Russia
Pharmaco-kinetics, dynamics and Drug Metabolism, Touro College of Pharmacy, USA
Professor of Nuclear Medicine, Faculty of Medicine and Surgery, University of Milan, Milan, Italy
Associate Professor at Department of Breast and Thyorid Surgey, Chongqing General Hospital, China
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