*Corresponding author:Joseph Miller, Department of Obstetrics, Gynecology and Minimally invasive surgery (MIS), Farmanieh Hospital, Tehran, Iran
Received: October 30, 2017; Published: November 08, 2017
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Endometriosis is a common benign gynecologic disease characterised by the presence of ectopic endometrial tissue outside the uterus. We present a brief review on the genetic factors underlying endometriosis, followed by a case report on concordant anatomical distribution of deep infiltrating endometriosis (DIE) in a pair of monozygotic (MZ) twins. To our knowledge, this is one of the first reported cases of DIE in MZ twins. The remarkable concordance and resemblance of deep disease involving the same anatomical sites, ovaries, pelvic floor and rectosigmoid colon in our MZ twins reiterates the role and impact of genetic factors in the pathogenesis of endometriosis.
Keywords: Deep Infiltrating Endometriosis; Sigmoid Resection; Monozygotic Twins; Genetics
Abbreviations: MZ: Mono Zygotic; DZ: Di Zygotic; DIE : Deep Infiltrating Endometriosis; IVP: Intravenous Pyelogram; TVS: Transvaginal Ultrasound; RES: Rectal Endoscopic Sonography; SMM: Smooth Muscle Metaplasia