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Research ArticleOpen Access

How Does Stathmin Destabilize Microtubules? A Root of Consciousness and Alzheimer’s Disease

Volume 1 - Issue 5

Majid Monajjemi*1, Farnoush Naghsh2 and Afshar Alihosseini1

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    • 1Department of Chemical engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran
    • 2Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran

    *Corresponding author: Majid Monajjemi, Department of Chemical engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran

Received: October 04, 2017;   Published: October 16, 2017

DOI: 10.26717/BJSTR.2017.01.000442

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Abstract

Alzheimer’s disease due to dementia and the memory brain that might be related to the microtubules disorder interrupt daily life. Alzheimer’s is a brain disease that causes a slow decline in concentrations, memory, thinking and reasoning skills. By this research we exhibited the important rules of stathmin destabilize microtubules as a root of this problem in view point of chemical molecular engineering.

Abbreviations: MT: Microyubule; SLD: Stathmin Like Domain; LOL: Localised Orbital Locator; ESP: Electro Static Potential; MAP: Microtubule Associated Proteins

Abstract| Introduction| Results And Discussion| Conclusion| References|