The Master Code of Biology: from Prions and Prions-like Invariants to the Self-assembly Thesis

Jean-Claude Perez *

Received: September 07, 2017;   Published: September 19, 2017

DOI: 10.26717/BJSTR.2017.01.000369

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Abstract

For more than 25 years, we have been looking for biomathematical laws controlling and structuring DNA, genes, proteins, chromosomes and genomes [1,2]. In 1997 we discovered a simple numerical law based solely on atomic masses, unifying the 3 languages of biology: DNA, RNA, and amino acids. This law, “The Master Code Of Biology” is published in 2009 in the book codex biogenesis [3] and then in 2015 in a reference article peer review [4]. In 2017 we publish different applications: HIV, SNPs, brain genetics [5-8]. On the other hand, at the beginning of the 2000s we studied the integrity of the Prions proteins (CJD, Creutzfeldt-Jakob disease), showing a common invariant bi-attractors in “W”, while the amyloid was characterized by a pattern in “V” shape. Since that time, biologists such as Claudio Soto have visually demonstrated in 3D the same biological form in horseshoe for the amyloid protein [9-13].

Keywords: Biomathematics; Master Code; DNA; Prions diseases; Genomics; Proteomics

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