β-HCG as a Tumor Biomarker with Special Reference to
Breast Cancer
Rafal Al Rawi*
DOI: 10.26717/BJSTR.2017.01.000234
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Author Information
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- Department of Pathology, Hawler Medical University, Iraq
Corresponding author:
Rafal Al-Rawi, Department of Pathology, College of Pharmacy, Hawler Medical University, Erbil, Iraq
Received: July 18, 2017; Published: August 01, 2017
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Abstract
Human chorionic gonadotropin (HCG) is a placental protein
hormone initially secreted by cells (syncitiotrophoblasts) from
the implanting conceptus. It supports the ovarian corpus luteum,
endometrial lining and consequently maintains pregnancy [1].
The hormone can be detected in blood and urine, as it is the basis
of many pregnancy tests. HCG plays many other roles including
stimulating the onset of fetal gonadal steroidogenesis, promotion
production of corpus luteal progesterone, immuno-suppression
and blockage of phagocytosis of invading trophoblast cells,
cytotrophoblast differentiation, growth and differentiation of fetal
organs [2].
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ISSN: 2574 -1241
