From Leiomyoma to Leiomyosarcoma: Role of Obesity
Abdeljabar El Andaloussi PhD MBA*
DOI: 10.26717/BJSTR.2017.01.000106
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Ob/Gyn Department, Medical college of Georgia, Augusta University, Georgia
*Corresponding author:
Abdeljabar El Andaloussi, Department of Experimental Medicine, University of Augusta, Georgia
Received: May 08, 2017 Published: May 23, 2017
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Abstract
Leiomyoma and leiomyosarcome (LMS) appear as two stages of tumor progression process of a transformed smooth muscle cell. Obesity
is a well-established risk factor of leiomyoma. The connection between both of them are not well understood. The involvement of obesity in
this transformation needs more investigation to be highlighted. Here, we discussed from a tumor immunology perspective, by focusing on the
microenvironment immunosuppression that, probably, allows LMS to escape the antitumor immune response.
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ISSN: 2574 -1241
